A man was shot on a city street before being rushed to hospital as police cordoned off three separate areas.
Emergency services were called to Weaver Street, in Walton, shortly after 4pm to reports that a man had been found injured.
The victim in his 20s was found by paramedics and police officers with a gunshot wound to his hip.
A short time later he was rushed to hospital for treatment as Merseyside Police launched an investigation into the attack.
Detectives believe the victim may have been shot in Breeze Hill before he managed to make his way to Weaver Street where he was found.
Three separates streets in the area have since been cordoned off by officers who are likely to be in the area for some time.
Police scenes are currently in place on Weaver Street, Olney Street and Queens Drive as house-to-hous enquiries take place.
Forensic officers are expected to arrive in the area later this evening.
A spokesperson for Merseyside Police said: "Detectives are investigating after a man was shot and injured in Walton this afternoon, Thursday 21 May.
"At 4.15pm, armed officers were called to Weaver Street to reports that a man in his 20s had been found with a gunshot injury.
"The victim was taken to hospital for assessment of a wound to his hip.
"Officers remain in the Weaver Street, Olney Street and Queens Drive area this evening carrying out house-to-house, forensic and CCTV enquiries.
Detective Chief Inspector Matt Smith said: “These are the very early stages of an investigation, and we’re looking to establish the exact circumstances.
"With that in mind, we’re particularly keen to speak to anyone in the area who may have seen this incident, or witnessed someone making off on foot or in a vehicle from the area.
“We believe that the victim may have been shot in Breeze Hill and made his way to where he was found, so if you live in or were passing by either of these locations and have information, CCTV, mobile phone or dashcam footage, make yourself known.
“Although the streets are quieter than usual, it is incredibly reckless to fire a gun in the daytime.
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“We’ve seen fewer incidents of this nature in the past few weeks but work continues in communities who feel the harm of serious crime.
"Recent arrests, seizures and disruption show the value of information from our communities, and we need that to continue so these people and their weapons are removed from the streets.
"Please contact us via our social media desk on Twitter @MerPolCC or Facebook 'Merseyside Police Contact Centre', with reference 713 of 21 May.
You can also contact the independent charity Crimestoppers anonymously on 0800 555 111, or via their online form at: https://crimestoppers-uk.org/give-information/give-information.