Boris Johnson will lead a press conference at Downing Street today, to mark the year anniversary of the first national lockdown.
The Prime Minister is expected to give a coronavirus update when addressing the nation at 5pm.
The press conference comes during the nation's day of reflection which includes a minute's silence, in remembrance of those who lost lives to the pandemic.
Boris Johnson will observe the moment of silence privately and others are encourage to do the same at 12pm today.
Arranged by Marie Curie, today monuments across the nation will also be illuminated yellow and churches and cathedrals will toll bells, light candles and offer a prayer.
Members of the public are being encouraged to join in by lighting candles at their doorstep or holding a light out at 8pm, tonight.
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Ahead of the day of reflection, Mr Johnson said: "The last 12 months has taken a huge toll on us all, and I offer my sincere condolences to those who have lost loved ones.
"Today, the anniversary of the first lockdown, is an opportunity to reflect on the past year – one of the most difficult in our country’s history.
"We should also remember the great spirit shown by our nation over this past year."
Health Secretary Matt Hancock said it had been "probably the hardest year in a generation" as he reflected on 12 months since the first coronavirus lockdown was introduced.
Asked how he would spend the day of reflection, Mr Hancock told Sky News: "I'll be working on the vaccine rollout and trying to get us out of this.
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"This has been an incredibly difficult year, probably the hardest year in a generation.
"Yet, we all search for hope as well, don't we? The hope is that we now have a route out of this and that route is possible because of the wonders of science and the scale of the vaccination programme."
Sir Lindsay Hoyle, Speaker of the House of Commons, said: "None of us has escaped the ordeal of Covid-19 – from the shock of having our liberty taken away, to the heartbreak of losing someone we loved.
"So, a year on, it is right that we take a moment to reflect on what we as a nation have been through; that we pay tribute to the many lives lost and the families that mourn them, and we say a big 'thank you' to our NHS staff who have worked so tirelessly on the front line caring for people in need."